A Model for the Electrically Stimulated Retina

S. Resatz and F. Rattay

Mathematical and Computer Modelling of Dynamical Systems, 2004, vol. 10, issue 2, 93-106

Abstract: Many blind people possess functioning bipolar and ganglion cells, which relay retinal input to the brain. In a two step procedure the excitation of electrically stimulated retinal cells is simulated: (i) the extracellular potential along the neural structure is computed (ii) the target cells are represented by compartment models. Membrane kinetics of the ganglion cells are evaluated with the Fohlmeister-Colman-Miller model. Transmembrane voltages of the bipolar cells are calculated for constant membrane conductance. In retinal ganglion cells the axons are the most excitable structures when stimulated with short cathodic pulses from epiretinal electrodes, whereas the axonal endings are the hot spots in bipolar cells.

Date: 2004
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DOI: 10.1080/13873950412331318080

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