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Stochastic analysis of autoregulatory gene expression dynamics

T. Ochiai and J. C. Nacher

Mathematical and Computer Modelling of Dynamical Systems, 2007, vol. 14, issue 4, 377-388

Abstract: In this work, the autoregulatory genetic module is investigated by using stochastic theory. We show here that the stochastic effect of the second order perturbation theory further reduces the fluctuation size of the gene expression level more than what is expected in deterministic methods. Furthermore, dynamical aspects of the system were investigated. In particular, we estimated the time needed to reach the equilibrium state.

Date: 2007
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DOI: 10.1080/13873950801972186

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