12-Year Experience Following Bone Marrow Transplantation with Emphasis on Acute and Chronic Leukemia

Robert Pokorski

North American Actuarial Journal, 1999, vol. 3, issue 3, 118-121

Abstract: New therapies for a serious impairment can be problematic from a risk classification perspective because insured lives data would not be available to provide guidance when these individuals later apply for insurance coverage. This uncertainty can be decreased by studying reports in the medical literature that observed large cohorts with the desired characteristics. This paper analyzes one of the world’s largest series, which asked the question “What is the long-term mortality and morbidity risk among patients who have already survived for five or more years after bone marrow transplantation?” Data indicate that medical advances have substantially improved prognosis. However, mortality and morbidity risks remain high compared to what would be expected in the general population, and data on a small number of long-term survivors suggest such risk might remain elevated indefinitely.

Date: 1999
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DOI: 10.1080/10920277.1999.10595838

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