The Role of IgA and IgG anti-transglutaminase antibodies in the diagnosis of celiac disease in children

Lacramioara Ilie, Andreea Popa, Larisa Goroftei, Elena Roxana Matache, Eliza Andreea Zaharia, Cristina Chelmu Voda, Lenuta Ambrose, Ionica Grigore, Daniela Mihalache, Gabriela Gurau and Doina Carina Voinescu
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Lacramioara Ilie: Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania & City Hospital Targu Bujor, Galati, Romania
Andreea Popa: Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania
Larisa Goroftei: Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania & Emergency Clinical Hospital for Children “Sf. Ioan” Galati, Romania
Elena Roxana Matache: Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania & Emergency Clinical Hospital for Children “Sf. Ioan” Galati, Romania
Eliza Andreea Zaharia: Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania & Emergency Clinical Hospital for Children “Sf. Ioan” Galati, Romania
Cristina Chelmu Voda: Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania
Lenuta Ambrose: Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania
Ionica Grigore: “Dunarea de Jos” University, Faculty of Medicine and Pharmacy Galati, Romania & Emergency County Hospital Braila, Romania
Daniela Mihalache: “Dunarea de Jos” University, Faculty of Medicine and Pharmacy Galati, Romania & Emergency County Hospital Braila, Romania
Gabriela Gurau: “Dunarea de Jos” University, Faculty of Medicine and Pharmacy Galati, Romania & Emergency Clinical Hospital for Children “Sf. Ioan” Galati, Romania
Doina Carina Voinescu: “Dunarea de Jos” University, Faculty of Medicine and Pharmacy Galati, Romania & Emergency Clinical Hospital “Sf. Ap.Andrei ” Galati, Romania

Technium BioChemMed: Journal of Multidisciplinary Research, Biology, Chemistry and Medicine ISSN 2734 - 7990, 2023, vol. 6, 56-59

Abstract: Aims: Diagnosing celiac disease in children presents various challenges for pediatricians in the various clinical stages. Thus, the diagnosis of cases increased significantly, although children did not always present symptoms or clinical signs of the disease. In support of the diagnosis, several factors come into play: screening, serological tests, awareness of the presence of celiac disease and the factors that favor its occurrence. Material and methods: We performed a retrospective study at the Pediatric Clinical Hospital "St. Ioan " Galati between January 1, 2014 and October 2022. In this study we included 2640 children with suggestive symptoms of celiac disease. Results: A number of 102 patients were diagnosed with celiac disease, recurrent abdominal pain being the most common symptom.

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:tec:bioche:ojs:10297

DOI: 10.47577/biochemmed.v6i.10297

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