Antibiotic resistance in urinary tract infection in children

Larisa Goroftei, Elena-Roxana Matache, Cosmin Răducu Răileanu, Lucian Peptine, Lăcrămioara Ilie, Tiberiu Mihalache, Ionica Grigore, Lăcrămiora Elena Lisă, Aurel Nechita, Gabriela Gurău and Andrei Neagu
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Larisa Goroftei: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania & 2Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, Romania & Emergency Clinical Hospital for Children “Sf. Ioan”, Galați, Romania
Elena-Roxana Matache: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania & 2Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, Romania & Emergency Clinical Hospital for Children “Sf. Ioan”, Galați, Romania
Cosmin Răducu Răileanu: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania & Emergency Clinical Hospital for Children “Sf. Ioan”, Galați, Romania
Lucian Peptine: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania & Emergency Clinical Hospital for Children “Sf. Ioan”, Galați, Romania
Lăcrămioara Ilie: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania & Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, Romania
Tiberiu Mihalache: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania
Ionica Grigore: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania & Emergency County Hospital Brăila, Brăila, Romania
Lăcrămiora Elena Lisă: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania & Department of pharmaceutical sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, Romania & Emergency Clinical Hospital for Children “Sf. Ioan”, Galați, Romania
Aurel Nechita: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania & Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, Romania & Emergency Clinical Hospital for Children “Sf. Ioan”, Galați, Romania
Gabriela Gurău: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania & 2Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, Romania & Emergency Clinical Hospital for Children “Sf. Ioan”, Galați, Romania
Andrei Neagu: „Dunărea de Jos” University, Doctoral School of Biomedical Sciences of Galați, Romania & Emergency County Hospital, "Sf. Andrei", Galati, Romania

Technium BioChemMed: Journal of Multidisciplinary Research, Biology, Chemistry and Medicine ISSN 2734 - 7990, 2023, vol. 4, issue 1, 25-32

Abstract: This retrospective study (November 2021-October 2022) aimed at identifying pathogen agents from positive urine cultures and tested their resistance to antibiotics at Emergency Clinical Hospital for Children “Sf. Ioan” in Galati, Romania. Included in this study were 167 bacterial strains and both Gram-positive and Gram-negative bacteria have been isolated. Most bacterial strains were Escherichia coli(56,28 %), Klebsiella pneumonia (12,57 %), Proteus mirabilis(8,38 %) and Enterococcus faecium (12,57 %). Others bacterial strains were: Pseudomonas aeruginosa (4,79 %), Staphylococcus saprophyticus (1,20 %), Staphylococcus epidermidis (0,59 %), Staphylococcus schleiferi (0,59 %), Staphylococcus aureus MSSA (0,59 %), Staphylococcus aureus MRSA (0,59 %), Streptococcus agalactiae (0,59 %), Enterobacter cloacae (0,59 %), Acinetobacter baumanii (0,59 %). Escherichia coli was the most frequent etiologic pathogen, being responsible for half of urinary tract infection (UTI) and the highest resistance in terms of pathogens was found among this bacteria. This research found a high rate of resistance to ampicilin and followed by co-trimoxazole, cephalosporines and aminoglycosides. Antimicrobial resistance in urinary tract infection in our days is a real threat that requires vigilant monitoring to be done.

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:tec:bioche:ojs:8026

DOI: 10.47577/biochemmed.v4i1.8026

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