Recent biopharmaceutical studies on the evolution of ophthalmic drugs

Luiza-Madalina Cima () and Ana-Maria Neculai ()
Additional contact information
Luiza-Madalina Cima: PhD; Pharmacist, Assistant, Faculty of Pharmacy, Titu Maiorescu University, Bucharest, Romania
Ana-Maria Neculai: PhD; Pharmacist, Assistant, Faculty of Medicine, Ovidius University of Constanta

Eximia Journal, 2022, vol. 4, issue 1, 134-143

Abstract: Ophthalmic pharmaceuticals have been one of the most important and widely developed fields of pharmaceutical technology for decades. The main reason for the continued interest of scientists in these forms of medicine is the issue of low bioavailability of the drug after application to the eyeball. The broad classification of ocular drug administration results in two categories: drugs concerned with anterior segment of the eye and drugs concerned with posterior segments of the eye. About 90% of ophthalmic formulations on the market are available in the form of eye drops and the sites of action are for diseases that occur in the anterior segment of the eye. For the release of ophthalmic drugs, the posterior segment of the eye is often a choice of interest to locate the drug, using new approaches. In this regard, this article highlights new developments in ophthalmic pharmaceutical formulations, such as in situ gel formulation, nanoparticles, liposomes, nanosuspension, microemulsion, eye inserts and so on and their progress to overcome problems associated with conventional dosage forms and also to improve bioavailability as well as support the release of the drug at the target site.

Keywords: ocular bioavailability; anterior and posterior segments; topical administration; nanotechnologies; viscosity enhancers; penetration enhancer (search for similar items in EconPapers)
Date: 2022
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://eximiajournal.com/index.php/eximia/article/view/114/62 (application/pdf)
https://eximiajournal.com/index.php/eximia/article/view/114 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:tec:eximia:v:4:y:2022:i:1:p:134-143

Access Statistics for this article

Eximia Journal is currently edited by Tanase Tasente

More articles in Eximia Journal from Plus Communication Consulting SRL
Bibliographic data for series maintained by Tanase Tasente ().