Effect of Gene Polymorphisms in Antioxidant Enzymes on Oxidative-Antioxidative Status in Young Men

Kotowska Jadwiga () and Jówko Ewa
Additional contact information
Kotowska Jadwiga: Józef Piłsudski University of Physical Education in Warsaw, Faculty of Physical Education and Health, Department of Natural Sciences, Biała Podlaska, Poland
Jówko Ewa: Józef Piłsudski University of Physical Education in Warsaw, Faculty of Physical Education and Health, Department of Natural Sciences, Biała Podlaska, Poland

Polish Journal of Sport and Tourism, 2020, vol. 27, issue 4, 7-13

Abstract: Introduction. The aim of the study was to evaluate the relationship between SOD1 +35A/C, SOD2 Val16Ala and GPx1 Pro198Leu gene polymorphisms and baseline level of oxidative-antioxidative status in blood. Material and methods.The study included 154 male students of physical education who participated in practical classes included in the study curriculum. Genotyping was carried out on genomic DNA using real-time PCR reaction with TaqMan assays. Also, fasting blood samples were analyzed for biochemical parameters including superoxide dismutase (SOD) activity in erythrocytes and the activity of glutathione peroxidase (GPx) in whole blood, as well as serum concentration of lipid hydroperoxides (LOOHs) and total antioxidant capacity (TAC) of serum. Results. SOD2 polymorphism had a significant effect on serum LOOHs concentration. Individuals with Val/Val genotype presented a significantly higher level of LOOHs than Val/Ala genotype carriers (p

Keywords: gene polymorphism; oxidative stress; lipid peroxidation; antioxidant enzymes (search for similar items in EconPapers)
Date: 2020
References: Add references at CitEc
Citations:

Downloads: (external link)
https://doi.org/10.2478/pjst-2020-0020 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:vrs:spotou:v:27:y:2020:i:4:p:7-13:n:1

DOI: 10.2478/pjst-2020-0020

Access Statistics for this article

Polish Journal of Sport and Tourism is currently edited by Ryszard Cieśliński

More articles in Polish Journal of Sport and Tourism from Sciendo
Bibliographic data for series maintained by Peter Golla ().