Robust Genetic Circuit Design: A Mixed H∞ and IQC Analysis

Ruijuan Chen, Wei Pan, Dongfei Fu and Xin He

Advances in Mathematical Physics, 2017, vol. 2017, issue 1

Abstract: This paper considers the problem of designing a genetic circuit which is robust to noise effect. To achieve this goal, a mixed H∞ and Integral Quadratic Constraints (IQC) approach is proposed. In order to minimize the effects of external noise on the genetic regulatory network in terms of H∞ norm, a design procedure of Hill coefficients in the promoters is presented. The IQC approach is introduced to analyze and guarantee the stability of the designed circuit.

Date: 2017
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https://doi.org/10.1155/2017/5757943

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Persistent link: https://EconPapers.repec.org/RePEc:wly:jnlamp:v:2017:y:2017:i:1:n:5757943

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