Nonlinearities in Drug Release Process from Polymeric Microparticles: Long‐Time‐Scale Behaviour

Elena Simona Bacaita, Costica Bejinariu, Borsos Zoltan, Catalina Peptu, Gabriela Andrei, Marcel Popa, Daniela Magop and Maricel Agop

Journal of Applied Mathematics, 2012, vol. 2012, issue 1

Abstract: A theoretical model of the drug release process from polymeric microparticles (a particular type of polymer matrix), through dispersive fractal approximation of motion, is built. As a result, the drug release process takes place through cnoidal oscillations modes of a normalized concentration field. This indicates that, in the case of long‐time‐scale evolutions, the drug particles assemble in a lattice of nonlinear oscillators occur macroscopically, through variations of drug concentration. The model is validated by experimental results.

Date: 2012
References: Add references at CitEc
Citations:

Downloads: (external link)
https://doi.org/10.1155/2012/653720

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:wly:jnljam:v:2012:y:2012:i:1:n:653720

Access Statistics for this article

More articles in Journal of Applied Mathematics from John Wiley & Sons
Bibliographic data for series maintained by Wiley Content Delivery ().