Symptom clusters in patients receiving haemodialysis: a systematic review of observational studies

Xiaoyi Cao, Lang Tian and Chen Lin

Journal of Clinical Nursing, 2017, vol. 26, issue 17-18, 2545-2557

Abstract: Aims and objectives To systematically review the common composition and the analytical methods performed to derive symptom clusters in patients receiving haemodialysis, and to examine their common predictive and outcome variables. Background Patients receiving haemodialysis may suffer from multiple and interactive symptoms simultaneously, which may impact their mortality, morbidity and quality of life. The composition of these symptom clusters varies depending on the different assessment tools, the variant evaluation timing points and the various statistical methodologies. A detailed review of existing studies is needed. Design A systematic review of observational studies. Methods Medline from 1950, CINAHL from 1960, Embase from 1980 and PsycINFO from 1967 as well as additional sources were searched. Content analysis was conducted to identify articles assessing the interrelationships of multiple symptoms. Results Five studies were identified. Several symptom clusters were identified with five common groupings being uraemic cluster, neuromuscular cluster, skin cluster, gastrointestinal cluster and energy/fatigue cluster. Four studies performed the principal component analysis with varimax rotation to extract symptom clusters and one study used correlation analysis. Different symptom assessment tools were used and each involving different array of symptoms. The predictive and outcome variables of symptom clusters also varied considerably. No studies have examined the longitudinal course and patients’ subjective experiences of symptom clusters. Conclusions Inconsistencies in the composition of symptom clusters across studies were identified due to inconsistencies in symptom assessment tools and statistical methodologies. Future studies should focus on an agreement about a robust and clinically relevant definition on symptom clusters; a multidimensional, valid and reliable symptom assessment tool; and an optimal analytical method in patients receiving haemodialysis. Relevance to clinical practice Knowledge of symptom clusters may contribute to understanding the aetiology and pathophysiology of multiple concurrent and interactive symptoms in patients receiving haemodialysis and exploring the effects of these symptoms on clinical outcomes.

Date: 2017
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://doi.org/10.1111/jocn.13644

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:wly:jocnur:v:26:y:2017:i:17-18:p:2545-2557

Access Statistics for this article

More articles in Journal of Clinical Nursing from John Wiley & Sons
Bibliographic data for series maintained by Wiley Content Delivery ().