SYNTHESIS AND CHARACTERIZATION OF THE ANTIMICROBIAL 4-AMINO-DECYLPYRIDINIUM BROMIDE CATIONIC SURFACTANT

Parag Madaan () and V. K. Tyagi ()
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Parag Madaan: Department of Oil and Paint Technology, Harcourt Butler Technological Institute, Kanpur 208002, India
V. K. Tyagi: Department of Oil and Paint Technology, Harcourt Butler Technological Institute, Kanpur 208002, India

Surface Review and Letters (SRL), 2008, vol. 15, issue 05, 531-536

Abstract: 4-Amino-decylpyridinium bromide (ADPBr), an antimicrobial surface active agent, was synthesized by quaternization of 4-aminopyridine (AP) with decyl bromide (DBr). The reaction was carried out at 1:1.2 molar ratio of reactants (4-aminopyridine and decyl bromide, respectively) at 200°C for 10 min. The maximum yield of the product was 74.6%. The structure of the synthesized product was characterized by using modern analytical techniques, such as FT-IR,1HNMR, and13CNMR. The antimicrobial activity of the salt was evaluated with minimum inhibition concentration method and showed good activity against gram-negative bacteria. The MIC of the salt was found to be 600 ppm for 2 × 104CFU/mL ofE. coli.

Keywords: Quaternary pyridinium salts; antimicrobial activity; characterization; synthesis; cationic surfactant (search for similar items in EconPapers)
Date: 2008
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DOI: 10.1142/S0218625X08011743

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