PREPARATION OF HYDROXYAPATITE COATING ON THE SURFACE OF HOLLOW GLASS MICROSPHERES USING A BIOMIMETIC PROCESS

Yan Jiao, Hai-Ying Yang, Ying-Long Zhang, Rong-Shuai Duan and Yu-Peng Lu ()
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Yan Jiao: Shandong Institute of Commerce and Technology, Jinan 250103, China
Hai-Ying Yang: Shandong Institute of Commerce and Technology, Jinan 250103, China
Ying-Long Zhang: Shandong Institute of Commerce and Technology, Jinan 250103, China
Rong-Shuai Duan: Shandong Institute of Commerce and Technology, Jinan 250103, China
Yu-Peng Lu: School of Materials Science and Engineering, Shandong University, Jinan 250061, P. R. China

Surface Review and Letters (SRL), 2014, vol. 21, issue 05, 1-6

Abstract: Microcarrier culture technology has attached more attention, especially for scale-up cell culture in the filed of tissue engineering. The present work introduces a microcarrier with hydroxyapatite (HA) on hollow glass microsphere. Hollow glass microspheres with a main composition ofSiO2(55–65 wt.%),Al2O3(26–35 wt.%), were pretreated byNaOH, on which hydroxyapatite coating was deposited by biomimetic process. The phase composition and morphology were characterized by X-ray diffractometer (XRD), Fourier transform infrared (FTIR) spectroscope, field emission scanning electron microscope (FE-SEM) and high resolution transmission electron microscope (HRTEM), respectively. The results showed that after immersion for 15 days in 1.5 SBF, the uniform and dense HA coating was formed and it has porous surface and low crystallinity.

Keywords: Hydroxyapatite coating; hollow; glass microsphere; biomimetic process (search for similar items in EconPapers)
Date: 2014
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DOI: 10.1142/S0218625X14500632

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