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EXPERIMENTAL STUDIES OF SURFACE-DRIVEN CAPILLARY FLOW IN PMMA MICROFLUIDIC DEVICES PREPARED BY DIRECT BONDING TECHNIQUE AND PASSIVE SEPARATION OF MICROPARTICLES IN MICROFLUIDIC LABORATORY-ON-A-CHIP SYSTEMS

Subhadeep Mukhopadhyay (), J. P. Banerjee, Ashish Mathur, M. Tweedie, J. A. McLaughlin and Susanta Sinha Roy
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Subhadeep Mukhopadhyay: Department of Electronics and Communication Engineering, Institute of Engineering and Management, Sector-5, Salt lake Electronics Complex, Kolkata 700091, West Bengal, India
J. P. Banerjee: Institute of Radio Physics and Electronics, University of Calcutta, Kolkata 700009, West Bengal, India
Ashish Mathur: Amity Institute of Nanotechnology, Amity University, Sector-125, Noida 201303, Uttar Pradesh, India
M. Tweedie: Nanotechnology and Integrated Bioengineering Centre, Jordanstown Campus, University of Ulster, Newtownabbey, BT37 OQB, Northern Ireland, United Kingdom
J. A. McLaughlin: Nanotechnology and Integrated Bioengineering Centre, Jordanstown Campus, University of Ulster, Newtownabbey, BT37 OQB, Northern Ireland, United Kingdom
Susanta Sinha Roy: Department of Physics, School of Natural Sciences, Shiv Nadar University, Gautam Budh Nagar 201314, Uttar Pradesh, India

Surface Review and Letters (SRL), 2015, vol. 22, issue 04, 1-11

Abstract: Proper bonding technique is investigated to achieve leakage-free surface-driven capillary flow in polymethylmethacrylate (PMMA) microfluidic devices. SU-8-based silicon stamp is fabricated by maskless lithography. This stamp is used to produce PMMA microchannel structure by hot embossing lithography. A direct bonding technique is mainly employed for leakage-free sealing inside PMMA microfluidic devices. The effect of surface wettability on surface-driven capillary flow is also investigated in PMMA microfluidic devices. The separation of polystyrene microparticles in PMMA laboratory-on-a-chip systems is investigated with the reduction of separation time by air dielectric barrier discharge (DBD) plasma processing of channel surfaces. This study is useful to fabricate the microfluidic laboratory-on-a-chip systems and to understand the surface-driven capillary flow.

Keywords: Hot embossing; direct bonding; laboratory-on-a-chip; capillary flow (search for similar items in EconPapers)
Date: 2015
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DOI: 10.1142/S0218625X1550050X

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