MESOPOROUS BIOACTIVE GLASSES: SYNTHESIS, CHARACTERIZATION, AND THEIR MEDICAL APPLICATIONS

Andualem Belachew Workie () and Shao-Ju Shih
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Andualem Belachew Workie: Department of Materials Science and Engineering, National Taiwan University of Science and Technology, No. 43, Sec. 4, Keelung Road, Da’an District, Taipei 10607, Taiwan, R. O. China
Shao-Ju Shih: Department of Materials Science and Engineering, National Taiwan University of Science and Technology, No. 43, Sec. 4, Keelung Road, Da’an District, Taipei 10607, Taiwan, R. O. China†Department of Fragrance and Cosmetic Science, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Sanmin District, Kaohsiung 80708, Taiwan, R. O. China

Surface Review and Letters (SRL), 2023, vol. 30, issue 04, 1-16

Abstract: Using biomaterials to create new technologies like sensors, electrodes, prosthetics, bioelectrodes, skin substitutes, and drug delivery systems is known as biotechnology. It is crucial for medical procedures like surgery, dentistry, prosthetics, biosensors, electrophoresis, bioelectricity, implantation, and many other fields of human endeavor. Mesoporous bioactive glasses (MBGs) are the main bioactive materials used for bone regeneration due to their large surface area and high pore content, which can increase bioactivity and facilitate new bone formation. Their large surface area and high pore volume result in higher surface chemical reactivity as compared to nonmesoporous bioactive glasses, hence they have a higher chemical reactivity. Cells were aligned on the surface of an implant in some other investigation when topographical characteristics were produced by electro-hydrodynamic printing with hydroxyapatite, and permanent small silica spheres are commonly used in biomedical applications for cell labeling or medication administration. Because of the inclusion of porosities in MBG matrixes, as well as their large surface area, the deposition of hydroxyl carbonate apatite is considerably accelerated. MBGs can be cultured in the laboratory with a variety of methods, depending on how they will be employed in medical therapy. Melt-quenching therapy, spray pyrolysis method, sol-gel manufacturing technique, spray drying process, and modified Stber method are some of these tactics. To guarantee that MBGs are appropriate for use in medical care, several characterization procedures like SEM, TEM, BET, XRD, etc. should be used in the laboratory.

Keywords: Biomaterials fabrication; hydroxyl carbonate apatite; drug delivery; medical implants; biocompatibility (search for similar items in EconPapers)
Date: 2023
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DOI: 10.1142/S0218625X23300046

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