Selection and Scheduling of Pharmaceutical Research Projects

Rainer Kolisch () and Konrad Meyer ()
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Rainer Kolisch: Technical University of Munich
Konrad Meyer: A.T. Kearney

Chapter Chapter 13 in Perspectives in Modern Project Scheduling, 2006, pp 321-344 from Springer

Abstract: Abstract This paper deals with the lead optimization phase of pharmaceutical research where a number of leads (molecules as a basis for potential drugs) are processed by different departments in order to optimize their biochemical characteristics. We depict each lead as a project and model the problem as a static multi-project selection and scheduling problem under resource constraints with the objective to maximize the weighted work performed. For solving the problem we propose two heuristics. We assess their performance in a computational study and we point out one dominant method. Furthermore we show the impact of problem parameters such as the extend to which projects can be crashed.

Keywords: Pharmaceutical R&D; Lead Optimization; Multi-Mode Resource-Constrained Project Scheduling; Heuristics (search for similar items in EconPapers)
Date: 2006
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Citations: View citations in EconPapers (16)

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Persistent link: https://EconPapers.repec.org/RePEc:spr:isochp:978-0-387-33768-5_13

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DOI: 10.1007/978-0-387-33768-5_13

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