Investigating Functional Cooperation in the Human Brain Using Simple Graph-Theoretic Methods

Michael L. Anderson (), Joan Brumbaugh and Aysu Şuben
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Michael L. Anderson: Franklin and Marshall College
Joan Brumbaugh: Franklin and Marshall College
Aysu Şuben: Franklin and Marshall College

Chapter Chapter 2 in Computational Neuroscience, 2010, pp 31-42 from Springer

Abstract: Abstract This chapter introduces a very simple analytic method for mining large numbers of brain imaging experiments to discover functional cooperation between regions. We then report some preliminary results of its application, illustrate some of the many future projects in which we expect the technique will be of considerable use (including a way to relate fMRI to EEG), and describe a research resource for investigating functional cooperation in the cortex that will be made publicly available through the lab web site. One significant finding is that differences between cognitive domains appear to be attributable more to differences in patterns of cooperation between brain regions, rather than to differences in which brain regions are used in each domain. This is not a result that is predicted by prevailing localization-based and modular accounts of the organization of the cortex.

Keywords: Cognitive Domain; Bold Signal; Brodmann Area; Brain Imaging Study; Activation Likelihood Estimate (search for similar items in EconPapers)
Date: 2010
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DOI: 10.1007/978-0-387-88630-5_2

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