Statistical Analysis of Genetic Data

Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
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Ton J. Cleophas: European Interuniversity College of Pharmaceutical Medicine Lyon
Aeilko H. Zwinderman: Academic Medical Center Amsterdam, Department Biostatistics and Epidemiology
Toine F. Cleophas: Technical University

Chapter Chapter 23 in Statistics Applied to Clinical Trials, 2006, pp 261-269 from Springer

Abstract: Abstract In 1860, the benchmark experiments of the monk Gregor Mendel led him to propose the existence of genes. The results of Mendel’s pea data were astoundingly close to those predicted by his theory. When we recently looked into Mendel’s pea data and performed a chi-square test, we had to conclude the the chi-square value was too small not to reject the null-hypothesis. this would mean that Mendel’s reported data were so close to what he expected that we could only conclude that he had somewhat fudged the data (Table 1).

Keywords: Genetic Data; Posterior Odds; Prior Odds; Healthy Offspring; Complex Disease Trait (search for similar items in EconPapers)
Date: 2006
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DOI: 10.1007/978-1-4020-4650-6_23

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