Executive Summary and Introduction

Marvin Cassman

Chapter CHAPTER 1 in Systems Biology, 2007, pp 1-13 from Springer

Abstract: Abstract Systems biology has become a major force in the past five to seven years. As with all new developments in science, the emergence of new approaches is a result of limitations in the existing model, in this case the limitations of molecular biology. For the past 40 years the paradigm for predicting phenotype has focused on single gene defects. This extraordinarily powerful approach has been the major contributor to an understanding of the function of individual genes and proteins. It seems less likely that it will yield an understanding of complex biological behavior, from individual cellular activities such as motility to the operation and integration of organ systems.

Keywords: System Biology; Biological Network; Executive Summary; Network Inference; Defense Advance Research Project Agency (search for similar items in EconPapers)
Date: 2007
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DOI: 10.1007/978-1-4020-5468-6_1

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