Application of Cox Regression with a Change Point in Clinical Studies

Xiaolong Luo, Gang Chen and James M. Boyett
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Xiaolong Luo: St. Jude Children’s Research Hospital, Department of Biostatistics
Gang Chen: St. Jude Children’s Research Hospital, Department of Biostatistics
James M. Boyett: St. Jude Children’s Research Hospital, Department of Biostatistics

A chapter in Lifetime Data: Models in Reliability and Survival Analysis, 1996, pp 213-217 from Springer

Abstract: Abstract Cox regression with an unknown change point and the corresponding large sample theory are discussed. We show how the results of this approach can be applied to computer-simulated data and to failure-time data from a large cohort of children treated at St. Jude Children’s Research Hospital for newly diagnosied acute lymphoblastic leukemia.

Keywords: Acute Lymphoblastic Leukemia; Change Point; FORTRAN Subroutine; Dental Abnormality; Hazard Rate Model (search for similar items in EconPapers)
Date: 1996
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Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-1-4757-5654-8_28

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DOI: 10.1007/978-1-4757-5654-8_28

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