Analysis of Data from a Cluster RCT

Jos W. R. Twisk ()
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Jos W. R. Twisk: Amsterdam UMC

Chapter Chapter 4 in Analysis of Data from Randomized Controlled Trials, 2021, pp 49-59 from Springer

Abstract: Abstract In this chapter the different methods for the analysis of a cluster RCT are discussed. The complexity of a cluster RCT is that there is dependency of data within the cluster which should be taken into account. This can be done by using a mixed model analysis. When there is more than one follow-up measurement in a cluster RCT, this leads to a so-called three-level structure in the data. The follow-up measurements are dependent within the subject, and the subjects are dependent within the cluster. This three-level structure slightly complicates the analyses.

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-3-030-81865-4_4

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DOI: 10.1007/978-3-030-81865-4_4

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