Stability of a Delayed Fractional Model for Viral Infection with Multiple Modes of Transmission and Humoral Immunity
Hanae Boukhrissi,
Fatima Assadiki,
Khalid Hattaf and
Fouad Lahmidi
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Hanae Boukhrissi: Hassan II University of Casablanca, Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Sciences Ben M’Sick
Fatima Assadiki: Hassan II University of Casablanca, Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Sciences Ben M’Sick
Khalid Hattaf: Centre Régional des Métiers de l’Education et de la Formation (CRMEF), Equipe de Recherche en Modélisation et Enseignement des Mathématiques (ERMEM)
Fouad Lahmidi: Hassan II University of Casablanca, Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Sciences Ben M’Sick
A chapter in Trends in Biomathematics: Modeling Health Across Ecology, Social Interactions, and Cells, 2025, pp 115-133 from Springer
Abstract:
Abstract In this chapter, we propose a new fractional model that describes the dynamics of viral infections like human immunodeficiency virus (HIV), hepatitis B virus (HBV), and SARS-CoV-2 which causes COVID-19. The proposed model includes three modes of transmission, two types of infected cells, one delay in viral production, and humoral immunity exerted by antibodies to neutralize viral particles. The equilibria and threshold parameters of the model are fully determined. Furthermore, the stability of equilibria is rigorously established.
Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-3-031-97461-8_6
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DOI: 10.1007/978-3-031-97461-8_6
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