Assessment of Health Related Quality of Life

Lawrence M. Friedman, Curt D. Furberg, David L. DeMets, David M. Reboussin, Christopher B. Granger, Michelle J. Naughton and Sally A. Shumaker
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Curt D. Furberg: Wake Forest School of Medicine, Division of Public Health Sciences
David L. DeMets: University of Wisconsin, Department Biostatistics and Medical Informatics
David M. Reboussin: Wake Forest School of Medicine, Department of Biostatistics
Christopher B. Granger: Duke University, Department of Medicine
Michelle J. Naughton: The Ohio State University
Sally A. Shumaker: Wake Forest School of Medicine

Chapter Chapter 13 in Fundamentals of Clinical Trials, 2015, pp 279-295 from Springer

Abstract: Abstract The major goal of randomized clinical trials is to determine the potential benefits and harms of an intervention. The benefits of most available interventions in medicine are symptom improvements. Thus, relief or reduction of symptoms is a common primary outcome in clinical trials (Chap. 3 ). Most of the adverse effects of interventions are also symptom-related (Chap. 12 ). Any changes in symptomatology are subjective and reported by trial participants. A special form of participant reported outcomes relate to various types of functioning, traditionally covered by the term health-related quality of life (HRQL) [1–4].

Date: 2015
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DOI: 10.1007/978-3-319-18539-2_13

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