Reporting and Interpreting of Results

Lawrence M. Friedman, Curt D. Furberg, David L. DeMets, David M. Reboussin and Christopher B. Granger
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Curt D. Furberg: Wake Forest School of Medicine, Division of Public Health Sciences
David L. DeMets: University of Wisconsin, Department Biostatistics and Medical Informatics
David M. Reboussin: Wake Forest School of Medicine, Department of Biostatistics
Christopher B. Granger: Duke University, Department of Medicine

Chapter Chapter 20 in Fundamentals of Clinical Trials, 2015, pp 479-499 from Springer

Abstract: Abstract The final phase in any experiment is to interpret and report the results. Finding the answer to a challenging question is the goal of any research endeavor. Proper communication of the results to clinicians also provides the basis for advances in medicine [1]. To communicate appropriately, investigators have to review their results critically and avoid the temptation to overinterpret benefit or underreport harm. They are in the privileged position of knowing the quality and limitations of the data better than anyone else. Therefore, they have the responsibility for presenting the results clearly and concisely, together with any issues that might bear on their interpretation. Investigators should devote adequate care, time and attention to this critical part of the conduct of clinical trials. We believe that a policy of “conservative” interpretation and reporting best serves science, public health, clinical medicine, and the interests of readers.

Date: 2015
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DOI: 10.1007/978-3-319-18539-2_20

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