Evolution of Clinical Trials Science

Steven Piantadosi ()
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Steven Piantadosi: Brigham and Women’s Hospital, Harvard Medical School, Department of Surgery, Division of Surgical Oncology

Chapter 2 in Principles and Practice of Clinical Trials, 2022, pp 21-33 from Springer

Abstract: Abstract The art of medicine took two millennia to establish the necessary groundwork for clinical trials which embody the scientific method for making fair comparisons of treatments. This resulted from a synthesis of opposing approaches to the acquisition of knowledge. Establishment of clinical trials in their basic form in the last half of the twentieth century continues to be augmented by advances in disparate fields such as research ethics, computerization, research administration and governance, and statistics.

Keywords: Design; Design evolution (search for similar items in EconPapers)
Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-3-319-52636-2_198

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DOI: 10.1007/978-3-319-52636-2_198

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