Clinical Epidemiology

Holger J. Schünemann and Gordon H. Guyatt
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Holger J. Schünemann: University at Buffalo, Departments of Medicine and Social & Preventive Medicine School of Medicine and Biomedical Sciences
Gordon H. Guyatt: McMaster University Health Sciences Centre, Departments of Medicine and Clinical Epidemiology & Biostatistics

Chapter III.8 in Handbook of Epidemiology, 2005, pp 1169-1223 from Springer

Abstract: Abstract This chapter will begin with providing a brief overview of the history of clinical epidemiology and describe its relation with evidence basedmedicine. Clinical epidemiology differs from classical epidemiology in that clinical epidemiology supports other basic medical sciences such as biochemistry, anatomy and physiology because it facilitates their application in research through formulation of sound clinical research methods and, thus, puts these disciplines into clinical context. Therefore, clinical epidemiology goes beyond clinical trials. We will describe this concept in the following paragraphs (see Sect. 8.1.1 through 8.1.3). The following sections include case scenarios that facilitate the introduction of the key concepts about developing clinical questions, using diagnostic tests, evaluating therapy, appraising systematic reviews, developing guidelines and making clinical decisions.

Keywords: Relative Risk Reduction; Absolute Risk Reduction; Clinical Epidemiology; Posttest Probability; Target Disorder (search for similar items in EconPapers)
Date: 2005
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DOI: 10.1007/978-3-540-26577-1_30

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