Stochastic Modelling and Experiments on Intra-Cellular Transport of Single-Headed Molecular Motors

Katsuhiro Nishinari, Yuko Kanayama, Yasushi Okada, Philip Greulich, Andreas Schadschneider and Debashish Chowdhury
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Katsuhiro Nishinari: University of Tokyo, Department of Aeronautics and Astronautics, Faculty of Engineering
Yuko Kanayama: University of Tokyo, Department of Aeronautics and Astronautics, Faculty of Engineering
Yasushi Okada: University of Tokyo, Department of Cell Biology and Anatomy, Graduate School of Medicine
Philip Greulich: Universität zu Köln, Institut für Theoretische Physik
Andreas Schadschneider: Universität zu Köln, Institut für Theoretische Physik
Debashish Chowdhury: Indian Institute of Technology, Department of Physics

A chapter in Traffic and Granular Flow’05, 2007, pp 263-268 from Springer

Abstract: Summary We develop a theoretical model of intra-cellular transport by mutually interacting molecular motors KIF1A that takes into account the hydrolysis of ATP explicitly. A remarkable feature of this model is that all its parameters can be directly determined from experimental data. Our results are in excellent quantitative agreement with the empirical data, and we also provide experimental evidence for the existence of domain walls in our in-vitro experiment.

Keywords: Domain Wall; Molecular Motor; Kinesin Motor; Asymmetric Simple Exclusion Process; Biochemical Cycle (search for similar items in EconPapers)
Date: 2007
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Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-3-540-47641-2_21

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DOI: 10.1007/978-3-540-47641-2_21

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