Traffic of Molecular Motors: From Theory to Experiments

Paolo Pierobon ()
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Paolo Pierobon: Institut Curie, CNRS UMR 168

A chapter in Traffic and Granular Flow ’07, 2009, pp 679-688 from Springer

Abstract: Summary Intracellular transport along microtubules or actin filaments, powered by molecular motors such as kinesins, dyneins or myosins, has been recently modeled using one-dimensional driven lattice gases. We discuss some generalizations of these models, that include extended particles and defects. We investigate the feasibility of single molecule experiments aiming to measure the average motor density and to locate the position of traffic jams by mean of a tracer particle. Finally, we comment on preliminary single molecule experiments performed in living cells.

Date: 2009
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Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-3-540-77074-9_76

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DOI: 10.1007/978-3-540-77074-9_76

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