Role of Serum High-Sensitivity C-Reactive Protein Level as Risk Factor in the Prediction of Coronary Artery Disease in Hyperglycemic Subjects

Md. Saiful Islam (), Rowshanul Habib (), Md. Rezaul Karim () and Tanzima Yeasmin ()
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Md. Saiful Islam: University of Rajshahi, Department of Biochemistry and Molecular Biology
Rowshanul Habib: University of Rajshahi, Department of Biochemistry and Molecular Biology
Md. Rezaul Karim: Islamic University, Department of Applied Nutrition and Food Technology
Tanzima Yeasmin: University of Rajshahi, Department of Biochemistry and Molecular Biology

A chapter in Data Science and SDGs, 2021, pp 123-134 from Springer

Abstract: Abstract In this study, we have evaluated the clinical value of the high-sensitivity C-reactive protein (hs-CRP) level in predicting the risk of coronary artery disease (CAD) in hyperglycemic subjects of Bangladesh. A total of 201 participants were selected for this study and fasting venous blood samples are collected from them for measuring fasting plasma glucose (FPG), serum total cholesterol (TC), triglycerides (TG), LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C), hs-CRP, apolipoprotein A-1, apolipoprotein B and lipoprotein(a). CAD risk of study subjects was estimated with the use of Framingham Risk Score (FRS). Out of 201, 91 study participants are found as normal fasting glucose (NFG), 56 as impaired fasting glucose (IFG) and 54 as diabetes mellitus. The average levels of TC, TG, LDL-C, HDL-C, TC/HDL-C ratio, apolipoprotein A-1, apolipoprotein B and lipoprotein(a) in NFG, IFG and diabetes are not significantly different between each group. Statistically significant (p

Keywords: Hyperglycemia; Cardiovascular disease; High-sensitivity C-reactive protein; Framingham risk score (search for similar items in EconPapers)
Date: 2021
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DOI: 10.1007/978-981-16-1919-9_10

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