EconPapers    
Economics at your fingertips  
 

Genetic Markers as Instrumental Variables

Stephanie von Hinke (), George Smith, Debbie Lawlor, Carol Propper and Frank Windmeijer ()

The Centre for Market and Public Organisation from Department of Economics, University of Bristol, UK

Abstract: The use of genetic markers as instrumental variables (IV) is receiving increasing attention from epidemiologists, economists, statisticians and social scientists. This paper examines the conditions that need to be met for genetic variants to be used as instruments. Although these have been discussed in the epidemiological, medical and statistical literature, they have not been well-defined in the economics and social science literature. The increasing availability of biomedical data however, makes understanding of these conditions crucial to the successful use of genotypes as instruments for modifiable risk factors. We combine the econometric IV literature with that from genetic epidemiology using a potential outcomes framework and review the IV conditions in the context of a social science application, examining the effect of child fat mass on academic performance.

Keywords: ALSPAC; Fat mass; Genetic Variants; Instrumental Variables; Mendelian Randomization; Potential Outcomes (search for similar items in EconPapers)
JEL-codes: C36 I1 J24 (search for similar items in EconPapers)
Date: 2011-10
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (6) Track citations by RSS feed

Downloads: (external link)
http://www.bristol.ac.uk/cmpo/publications/papers/2011/wp274.pdf (application/pdf)

Related works:
Journal Article: Genetic markers as instrumental variables (2016) Downloads
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:bri:cmpowp:11/274

Access Statistics for this paper

More papers in The Centre for Market and Public Organisation from Department of Economics, University of Bristol, UK Contact information at EDIRC.
Bibliographic data for series maintained by ().

 
Page updated 2019-10-14
Handle: RePEc:bri:cmpowp:11/274