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Does NICE influence the adoption and uptake of generics in the UK?

Victoria Serra-Sastre, Simona Bianchi, Jorge Mestre-Ferrandiz and O’Neill, Phill

LSE Research Online Documents on Economics from London School of Economics and Political Science, LSE Library

Abstract: The aim of this paper is to examine generic competition in the UK, with a special focus on the role of Health Technology Assessment (HTA) on generic market entry and diffusion. In the UK, where no direct price regulation on pharmaceuticals exists, HTA has a leading role for recommending the use of medicines providing a non-regulatory aspect that may influence the dynamics in the generic market. The paper focuses on the role of Technology Appraisals issued by the National Institute for Health and Care Excellence (NICE). We follow a two-step approach. First, we examine the probability of generic entry. Second, conditional on generic entry, we examine the determinants of generic market share. We use data from IQVIA British Pharmaceutical Index (BPI) for the primary care market for 60 products that lost patent between 2003 and 2012. Our results suggest that market size remains one of the main drivers of generic entry. After controlling for market size, intermolecular substitution and difficulty of manufacturing increase the likelihood of generic entry. After generic entry, our estimates suggest that generic market share is highly state dependent. Our findings also suggest that while NICE recommendations do influence generic uptake, there is only marginal evidence they affect generic entry.

Keywords: generic competition; generic entry; market share; NICE (search for similar items in EconPapers)
JEL-codes: I11 I18 (search for similar items in EconPapers)
Pages: 14 pages
Date: 2021-03-01
New Economics Papers: this item is included in nep-com, nep-hea and nep-reg
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Published in European Journal of Health Economics, 1, March, 2021, 22(2), pp. 229 - 242. ISSN: 1618-7598

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