Bayesian epidemic models for spatially aggregated count data

Chrysovalantis Malesios, N Demiris, K Kalogeropoulos and I Ntzoufras

LSE Research Online Documents on Economics from London School of Economics and Political Science, LSE Library

Abstract: Epidemic data often possess certain characteristics, such as the presence of many zeros, the spatial nature of the disease spread mechanism, environmental noise, serial correlation and dependence on time varying factors. This paper addresses these issues via suitable Bayesian modelling. In doing so we utilise a general class of stochastic regression models appropriate for spatio-temporal count data with an excess number of zeros. The developed regression framework does incorporate serial correlation and time varying covariates through an Ornstein Uhlenbeck process formulation. In addition, we explore the effect of different priors, including default options and variations of mixtures of g-priors. The effect of different distance kernels for the epidemic model component is investigated. We proceed by developing branching process-based methods for testing scenarios for disease control, thus linking traditional epidemiological models with stochastic epidemic processes, useful in policy-focused decision making. The approach is illustrated with an application to a sheep pox dataset from the Evros region, Greece.

Keywords: Bayesian modelling; Bayesian variable selection; branching process; epidemic extinction; g-prior; spatial kernel; disease control (search for similar items in EconPapers)
JEL-codes: C1 (search for similar items in EconPapers)
Date: 2017-06-12
New Economics Papers: this item is included in nep-ecm, nep-hea, nep-knm and nep-ore
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Published in Statistics in Medicine, 12, June, 2017, 36(20), pp. 3216-3230. ISSN: 0277-6715

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