Impact of a malaria intervention package in schools on Plasmodium infection, anaemia and cognitive function in schoolchildren in Mali: a pragmatic cluster-randomised trial

Siân Clarke, Saba Rouhani, Seybou Diarra, Renion Saye, Modibo Bamadio, Rebecca Jones, Diahara Traore, Klenon Traore, Matthew Jukes (), Josselin Thuilliez, Simon Brooker, Natalie Roschnik and Moussa Sacko
Additional contact information
Siân Clarke: Faculty of Infectious and Tropical Diseases - LSHTM - London School of Hygiene and Tropical Medicine
Saba Rouhani: Faculty of Infectious and Tropical Diseases - LSHTM - London School of Hygiene and Tropical Medicine, Save the Children, Bamako, Mali
Seybou Diarra: Save the Children, Bamako, Mali
Renion Saye: INSP - Institut National de Santé Publique [Bamako] = National Institute of Research on Public Health
Modibo Bamadio: Save the Children, Bamako, Mali
Rebecca Jones: Faculty of Infectious and Tropical Diseases - LSHTM - London School of Hygiene and Tropical Medicine
Diahara Traore: Ministry of Health, Programme National de Lutte contre le Paludisme, Mali
Klenon Traore: Ministry of Health, Programme National de Lutte contre le Paludisme, Mali
Matthew Jukes: National Institute for Environmental Health Sciences Research Triangle Park - National Institute for Environmental Health Sciences Research Triangle Park
Simon Brooker: Faculty of Infectious and Tropical Diseases - LSHTM - London School of Hygiene and Tropical Medicine
Natalie Roschnik: Save the Children, Bamako, Mali
Moussa Sacko: INSP - Institut National de Santé Publique [Bamako] = National Institute of Research on Public Health

Université Paris1 Panthéon-Sorbonne (Post-Print and Working Papers) from HAL

Abstract: Background : School-aged children are rarely targeted by malaria control programmes, yet the prevalence of Plasmodium infection in primary school children often exceeds that seen in younger children and could affect haemoglobin concentration and school performance. Methods : A cluster-randomised trial was carried out in 80 primary schools in southern Mali to evaluate the impact of a school-based malaria intervention package. Intervention schools received two interventions sequentially: (1) teacher-led participatory malaria prevention education, combined with distribution of long-lasting insecticidal nets (LLINs), followed 7 months later at the end of the transmission season by (2) mass delivery of artesunate and sulfadoxine-pyrimethamine administered by teachers, termed intermittent parasite clearance in schools (IPCs). Control schools received LLINs as part of the national universal net distribution programme. The impact of the interventions on malaria and anaemia was evaluated over 20 months using cross-sectional surveys in a random subset of 38 schools(all classes), with a range of cognitive measures (sustained attention, visual search, numeracy, vocabulary and writing) assessed in a longitudinal cohort of children aged 9–12 years in all 80 schools.

Keywords: intermittent preventive treatment; IPT; intermittent parasite clearance; IPC; asymptomatic; gametocytes; Mali; malaria; anaemia; cognition; schoolchildren; schools; insecticide-treated nets; ITNs. LLINs (search for similar items in EconPapers)
Date: 2017-06-28
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Published in BMJ Global Health, 2017, 2 (2), pp.e000182. ⟨10.1136/bmjgh-2016-000182⟩

There are no downloads for this item, see the EconPapers FAQ for hints about obtaining it.

Related works:
Working Paper: Impact of a malaria intervention package in schools on Plasmodium infection, anaemia and cognitive function in schoolchildren in Mali: a pragmatic cluster-randomised trial (2017)
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:hal:cesptp:halshs-01674689

DOI: 10.1136/bmjgh-2016-000182

Access Statistics for this paper

More papers in Université Paris1 Panthéon-Sorbonne (Post-Print and Working Papers) from HAL
Bibliographic data for series maintained by CCSD ().