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Sub-Saharan Africa and hepatitis C: challenges and insights regarding the implementation of innovative diagnostics

Afrique sub-saharienne et hépatite C: défis et perspectives de la mise en œuvre opérationnelle d’outils diagnostiques innovants

Léa Duchesne () and Victor Duchesne
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Léa Duchesne: iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique - UPMC - Université Pierre et Marie Curie - Paris 6 - INSERM - Institut National de la Santé et de la Recherche Médicale

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Abstract: With the advent of novel treatments with a cure rate higher than 90%, the elimination of chronic hepatitis C has become achievable. In developing countries, the chronic lack of diagnostic facilities represents a barrier to their spread. The development of a viremic test suitable to decentralized settings appears to be a crucial point of the fight against hepatitis C. Many innovations, based on the principle of frugal innovations, could enable the creation of such a test. Despite their potential, only a small number of these technologies have been made commercially available. The inherent difficulties of the innovation process in developing countries, as well as the lack of collaboration between the different research fields involved during the design phase of the prototypes (manufacturing, integration of feedbacks) and the marketing phase (regulation, distribution, sustainability), reinforce the difficulty of implementing innovative diagnostics.

Date: 2018
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Published in Journal de Gestion et d’Économie Médicales, Editions ESKA, 2018, 36 (5-6), pp.315-329. ⟨10.3917/jgem.185.0315.⟩

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DOI: 10.3917/jgem.185.0315.

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