Absenteeism and indirect costs during the year following the diagnosis of an operable breast cancer: A prospective multicentric cohort study

Clement Ferrier, Clémence Thébaut, Pierre Lévy, Sandrine Baffert, Bernard Asselain, Roman Rouzier () and Delphine Hequet
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Clement Ferrier: Département d'Oncologie Chirurgicale [Institut Curie] - Institut Curie [Paris]
Clémence Thébaut: Legos - Laboratoire d'Economie et de Gestion des Organisations de Santé - Université Paris Dauphine-PSL - PSL - Université Paris Sciences et Lettres, LEDa - Laboratoire d'Economie de Dauphine - IRD - Institut de Recherche pour le Développement - Université Paris Dauphine-PSL - PSL - Université Paris Sciences et Lettres - CNRS - Centre National de la Recherche Scientifique
Pierre Lévy: Legos - Laboratoire d'Economie et de Gestion des Organisations de Santé - Université Paris Dauphine-PSL - PSL - Université Paris Sciences et Lettres, LEDa - Laboratoire d'Economie de Dauphine - IRD - Institut de Recherche pour le Développement - Université Paris Dauphine-PSL - PSL - Université Paris Sciences et Lettres - CNRS - Centre National de la Recherche Scientifique
Sandrine Baffert: CEMKA-EVAL - CEMKA-EVAL
Bernard Asselain: Center for Clinical Epidemiology and Biostatistics - Abramson Cancer Center - Perelman School of Medicine - University of Pennsylvania
Roman Rouzier: Department of Surgery [Saint-Cloud] - Institut Curie [Paris]
Delphine Hequet: Department of Surgery [Saint-Cloud] - Institut Curie [Paris]

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Abstract: Background : Diseases consequence on individual work as much as consequences of being absent from work are matters of interest for decision makers. Methods : We analyzed lengths of absenteeism and related indirect costs for patients with a paid activity in the year following the diagnosis of early stage breast cancer, in the prospective OPTISOINS01 cohort. Both human capital and friction costs approach were considered for the valuation of lost working days (LWD). For the analysis, the friction period was estimated from recent French data. The statistical analysis included simple and multiple linear regression to search for the determinants of absenteeism and indirect costs. Results : 93 % of the patients had at least one period of sick leave, with on average 2 period and 186 days of sick leave. 24 % of the patients had a part-time resumption after their sick leave periods, during 114 days on average (i.e. 41 LWD). Estimated indirect costs were 22,722.00 € and 7,724.00 € per patient, respectively for the human capital and the friction cost approach. In the multiple linear regression model, factors associated with absenteeism were: the invasive nature of the tumor (p = .043), a mastectomy (p = .038), a surgery revision (p = .002), a chemotherapy (p = .027), being a manager (p = .025) or a craftsman (p = .005). Conclusion : Breast cancer lead to important lengths of absenteeism in the year following the diagnosis, but almost all patients were able to return to work. Using the friction cost or the human capital approach in the analysis led to an important gap in the results, highlighting the importance of considering both for such studies.

Keywords: Health economics; Breast cancer; Indirect costs; Absenteeism; Economic burden (search for similar items in EconPapers)
Date: 2021-06
Note: View the original document on HAL open archive server: https://hal.science/hal-03120133v1
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Published in Journal of Gynecology Obstetrics and Human Reproduction, 2021, 50 (6), pp.101871. ⟨10.1016/j.jogoh.2020.101871⟩

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Persistent link: https://EconPapers.repec.org/RePEc:hal:journl:hal-03120133

DOI: 10.1016/j.jogoh.2020.101871

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