Reducing the cost of managing patients with atrial fibrillation undergoing percutaneous coronary intervention with stenting

Roxana Mehran, Birgit Vogel and Pierre Lévy
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Roxana Mehran: Mount Sinai Medical Center - MSSM - Icahn School of Medicine at Mount Sinai [New York], Cardiovascular Research Foundation - Cardiovascular Research Foundation
Birgit Vogel: Mount Sinai Medical Center - MSSM - Icahn School of Medicine at Mount Sinai [New York]
Pierre Lévy: Legos - Laboratoire d'Economie et de Gestion des Organisations de Santé - Université Paris Dauphine-PSL - PSL - Université Paris Sciences et Lettres, LEDa - Laboratoire d'Economie de Dauphine - IRD - Institut de Recherche pour le Développement - Université Paris Dauphine-PSL - PSL - Université Paris Sciences et Lettres - CNRS - Centre National de la Recherche Scientifique

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Abstract: Patients undergoing percutaneous coronary intervention (PCI) have an increased risk of both ischemic events and bleeding complications resulting from antithrombotic therapy. These events are particularly common in patients with a concomitant indication for oral anticoagulation, such as those with atrial fibrillation, and are associated with a substantial healthcare resource burden. Advances in procedural aspects of PCI have led to marked improvements in outcomes and a consequent reduction in the costs resulting from PCI-associated complications. Furthermore, recent randomized clinical trials have investigated the optimal antithrombotic strategy in the specific case of patients with atrial fibrillation undergoing PCI, leading to a shift toward the tailoring of antithrombotic therapy according to the patient's individual stroke and bleeding risks. Here we review these recent advances, with a particular focus on the improvements in antithrombotic strategies offered by the non-vitamin K antagonist oral anticoagulants

Keywords: Atrial fibrillation; Cost; Percutaneous coronary intervention; Bleeding complications; Thrombosis (search for similar items in EconPapers)
Date: 2021
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Published in journal of Cardiology, 2021, 77 (1), ⟨10.1016/j.jjcc.2020.07.018⟩

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Persistent link: https://EconPapers.repec.org/RePEc:hal:journl:hal-03120565

DOI: 10.1016/j.jjcc.2020.07.018

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