Advancing tools for human early lifecourse exposome research and translation (ATHLETE)

Martine Vrijheid (), Xavier Basagaña, Juan Gonzalez, Vincent Jaddoe, Genon Jensen, Hector Keun, Rosemary Mceachan, Joana Porcel, Valerie Siroux, Morris Swertz, Cathrine Thomsen, Gunn Marit Aasvang, Sandra Andrušaitytė, Karine Angeli (), Demetris Avraam, Ferran Ballester, Paul Burton, Mariona Bustamante, Maribel Casas, Leda Chatzi, Cécile Chevrier (), Natacha Cingotti, David Conti, Amélie Crépet (), Payam Dadvand, Liesbeth Duijts, Esther van Enckevort, Ana Esplugues, Serena Fossati, Ronan Garlantézec (), María Dolores Gómez Roig, Regina Grazuleviciene, Kristine Gützkow, Mònica Guxens, Sido Haakma, Ellen Hessel, Lesley Hoyles, Eleanor Hyde, Jana Klanova, Jacob van Klaveren, Andreas Kortenkamp, Laurent Le Brusquet (), Ivonne Leenen, Aitana Lertxundi, Nerea Lertxundi, Christos Lionis, Sabrina Llop, Maria-Jose Lopez-Espinosa, Sarah Lyon-Caen, Lea Maitre, Dan Mason, Sandrine Mathy, Edurne Mazarico, Tim Nawrot, Mark Nieuwenhuijsen, Rodney Ortiz, Marie Pedersen, Josep Perelló, Míriam Pérez-Cruz, Claire Philippat, Pavel Piler, Costanza Pizzi, Joane Quentin, Lorenzo Richiardi, Adrian Rodriguez, Theano Roumeliotaki, José Manuel Sabin Capote, Leonardo Santiago, Susana Santos, Alexandros Siskos, Katrine Strandberg-Larsen, Nikos Stratakis, Jordi Sunyer, Arthur Tenenhaus (), Marina Vafeiadi, Rebecca Wilson, John Wright, Tiffany Yang and Remy Slama
Additional contact information
Martine Vrijheid: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Xavier Basagaña: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Juan Gonzalez: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Vincent Jaddoe: The Generation R Study Group - Erasmus MC - Erasmus University Medical Center [Rotterdam], Erasmus MC - Erasmus University Medical Center [Rotterdam]
Genon Jensen: HEAL - Health & Environment Alliance
Hector Keun: Imperial College London
Rosemary Mceachan: BIHR - Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
Joana Porcel: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Valerie Siroux: IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) - CHUGA - Centre Hospitalier Universitaire [CHU Grenoble] - INSERM - Institut National de la Santé et de la Recherche Médicale - EFS - Etablissement français du sang - Auvergne-Rhône-Alpes - CNRS - Centre National de la Recherche Scientifique - UGA - Université Grenoble Alpes
Morris Swertz: UMCG - University Medical Center Groningen [Groningen]
Cathrine Thomsen: NIPH - Norwegian Institute of Public Health [Oslo]
Gunn Marit Aasvang: NIPH - Norwegian Institute of Public Health [Oslo]
Sandra Andrušaitytė: VDU - Vytautas Magnus University - Vytauto Didziojo Universitetas
Karine Angeli: DER - Direction de l'Evaluation des Risques - ANSES - Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail
Demetris Avraam: Newcastle University [Newcastle]
Ferran Ballester: FISABIO - Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana [Espagne], CIBERESP - Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública = Consortium for Biomedical Research of Epidemiology and Public Health, UV - Universitat de València = University of Valencia, Universitat Jaume I = Jaume I University
Paul Burton: Newcastle University [Newcastle]
Mariona Bustamante: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Maribel Casas: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Leda Chatzi: USC - University of Southern California
Cécile Chevrier: Irset - Institut de recherche en santé, environnement et travail - UA - Université d'Angers - UR - Université de Rennes - EHESP - École des Hautes Études en Santé Publique [EHESP] - INSERM - Institut National de la Santé et de la Recherche Médicale - Biosit : Biologie - Santé - Innovation Technologique - Structure Fédérative de Recherche en Biologie et Santé de Rennes
Natacha Cingotti: HEAL - Health & Environment Alliance
David Conti: USC - University of Southern California
Amélie Crépet: DER - Direction de l'Evaluation des Risques - ANSES - Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail
Payam Dadvand: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Liesbeth Duijts: Erasmus MC - Erasmus University Medical Center [Rotterdam]
Esther van Enckevort: UMCG - University Medical Center Groningen [Groningen]
Ana Esplugues: FISABIO - Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana [Espagne], UV - Universitat de València = University of Valencia, CIBERESP - Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública = Consortium for Biomedical Research of Epidemiology and Public Health
Serena Fossati: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Ronan Garlantézec: EHESP - École des Hautes Études en Santé Publique [EHESP], Irset - Institut de recherche en santé, environnement et travail - UA - Université d'Angers - UR - Université de Rennes - EHESP - École des Hautes Études en Santé Publique [EHESP] - INSERM - Institut National de la Santé et de la Recherche Médicale - Biosit : Biologie - Santé - Innovation Technologique - Structure Fédérative de Recherche en Biologie et Santé de Rennes, Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
María Dolores Gómez Roig: Institut de Recerca Pediàtrica Hospital Sant Joan de Déu [Barcelona, Spain]
Regina Grazuleviciene: VDU - Vytautas Magnus University - Vytauto Didziojo Universitetas
Kristine Gützkow: NIPH - Norwegian Institute of Public Health [Oslo]
Mònica Guxens: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], CIBERESP - Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública = Consortium for Biomedical Research of Epidemiology and Public Health, UPF - Universitat Pompeu Fabra [Barcelona], Erasmus MC - Erasmus University Medical Center [Rotterdam]
Sido Haakma: UMCG - University Medical Center Groningen [Groningen]
Ellen Hessel: RIVM - National Institute for Public Health and the Environment [Bilthoven]
Lesley Hoyles: Nottingham Trent University
Eleanor Hyde: UMCG - University Medical Center Groningen [Groningen]
Jana Klanova: RECETOX / MUNI - Research Centre for Toxic Compounds in the Environment [Brno] - SCI / MUNI - Faculty of Science [Brno] - MUNI - Masaryk University [Brno]
Jacob van Klaveren: RIVM - National Institute for Public Health and the Environment [Bilthoven]
Andreas Kortenkamp: Brunel University London [Uxbridge]
Laurent Le Brusquet: NeuroPSI - Institut des Neurosciences Paris-Saclay - Université Paris-Saclay - CNRS - Centre National de la Recherche Scientifique
Ivonne Leenen: HEAL - Health & Environment Alliance
Aitana Lertxundi: UPV / EHU - Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne], CIBERESP - Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública = Consortium for Biomedical Research of Epidemiology and Public Health, BioDonostia Health Research Institute = Instituto de Investigación Sanitaria Biodonostia
Nerea Lertxundi: UPV / EHU - Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne], BioDonostia Health Research Institute = Instituto de Investigación Sanitaria Biodonostia
Christos Lionis: UOC - University of Crete [Heraklion]
Sabrina Llop: CIBERESP - Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública = Consortium for Biomedical Research of Epidemiology and Public Health, Universitat Jaume I = Jaume I University
Maria-Jose Lopez-Espinosa: CIBERESP - Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública = Consortium for Biomedical Research of Epidemiology and Public Health, Universitat Jaume I = Jaume I University, UV - Universitat de València = University of Valencia
Sarah Lyon-Caen: IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) - CHUGA - Centre Hospitalier Universitaire [CHU Grenoble] - INSERM - Institut National de la Santé et de la Recherche Médicale - EFS - Etablissement français du sang - Auvergne-Rhône-Alpes - CNRS - Centre National de la Recherche Scientifique - UGA - Université Grenoble Alpes
Lea Maitre: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Dan Mason: BIHR - Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
Edurne Mazarico: Institut de Recerca Pediàtrica Hospital Sant Joan de Déu [Barcelona, Spain]
Tim Nawrot: UHasselt - Hasselt University, KU Leuven - Catholic University of Leuven = Katholieke Universiteit Leuven
Mark Nieuwenhuijsen: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Rodney Ortiz: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Marie Pedersen: UCPH - University of Copenhagen = Københavns Universitet
Josep Perelló: Bettair Cities SL, Barcelona
Míriam Pérez-Cruz: Institut de Recerca Pediàtrica Hospital Sant Joan de Déu [Barcelona, Spain]
Claire Philippat: IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) - CHUGA - Centre Hospitalier Universitaire [CHU Grenoble] - INSERM - Institut National de la Santé et de la Recherche Médicale - EFS - Etablissement français du sang - Auvergne-Rhône-Alpes - CNRS - Centre National de la Recherche Scientifique - UGA - Université Grenoble Alpes
Pavel Piler: MUNI - Masaryk University [Brno]
Costanza Pizzi: Department of Oncology [University of Turin] - UNITO - Università degli studi di Torino = University of Turin
Joane Quentin: IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) - CHUGA - Centre Hospitalier Universitaire [CHU Grenoble] - INSERM - Institut National de la Santé et de la Recherche Médicale - EFS - Etablissement français du sang - Auvergne-Rhône-Alpes - CNRS - Centre National de la Recherche Scientifique - UGA - Université Grenoble Alpes
Lorenzo Richiardi: Department of Oncology [University of Turin] - UNITO - Università degli studi di Torino = University of Turin
Adrian Rodriguez: Bettair Cities SL, Barcelona
Theano Roumeliotaki: UOC - University of Crete [Heraklion]
José Manuel Sabin Capote: Bettair Cities SL, Barcelona
Leonardo Santiago: Bettair Cities SL, Barcelona
Susana Santos: Erasmus University Rotterdam
Alexandros Siskos: Imperial College London
Katrine Strandberg-Larsen: ITU - IT University of Copenhagen
Nikos Stratakis: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], USC - University of Southern California
Jordi Sunyer: ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona], UPF - Universitat Pompeu Fabra [Barcelona]
Arthur Tenenhaus: L2S - Laboratoire des signaux et systèmes - CentraleSupélec - Université Paris-Saclay - CNRS - Centre National de la Recherche Scientifique
Marina Vafeiadi: UOC - University of Crete [Heraklion]
Rebecca Wilson: University of Liverpool
John Wright: BIHR - Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
Tiffany Yang: BIHR - Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
Remy Slama: IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) - CHUGA - Centre Hospitalier Universitaire [CHU Grenoble] - INSERM - Institut National de la Santé et de la Recherche Médicale - EFS - Etablissement français du sang - Auvergne-Rhône-Alpes - CNRS - Centre National de la Recherche Scientifique - UGA - Université Grenoble Alpes

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Abstract: Early life stages are vulnerable to environmental hazards and present important windows of opportunity for lifelong disease prevention. This makes early life a relevant starting point for exposome studies. The Advancing Tools for Human Early Lifecourse Exposome Research and Translation (ATHLETE) project aims to develop a toolbox of exposome tools and a Europe-wide exposome cohort that will be used to systematically quantify the effects of a wide range of community- and individual-level environmental risk factors on mental, cardiometabolic, and respiratory health outcomes and associated biological pathways, longitudinally from early pregnancy through to adolescence. Exposome tool and data development include as follows: (1) a findable, accessible, interoperable, reusable (FAIR) data infrastructure for early life exposome cohort data, including 16 prospective birth cohorts in 11 European countries; (2) targeted and nontargeted approaches to measure a wide range of environmental exposures (urban, chemical, physical, behavioral, social); (3) advanced statistical and toxicological strategies to analyze complex multidimensional exposome data; (4) estimation of associations between the exposome and early organ development, health trajectories, and biological (metagenomic, metabolomic, epigenetic, aging, and stress) pathways; (5) intervention strategies to improve early life urban and chemical exposomes, co-produced with local communities; and (6) child health impacts and associated costs related to the exposome. Data, tools, and results will be assembled in an openly accessible toolbox, which will provide great opportunities for researchers, policymakers, and other stakeholders, beyond the duration of the project. ATHLETE's results will help to better understand and prevent health damage from environmental exposures and their mixtures from the earliest parts of the life course onward.

Keywords: Exposome; Child health; Adolescent health; Exposure assessment; Early life (search for similar items in EconPapers)
Date: 2021-10
New Economics Papers: this item is included in nep-env
Note: View the original document on HAL open archive server: https://hal.science/hal-03419303v1
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Published in Journal of Exposure Analysis and Environmental Epidemiology, 2021, 5 (5), pp.e166. ⟨10.1097/EE9.0000000000000166⟩

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Persistent link: https://EconPapers.repec.org/RePEc:hal:journl:hal-03419303

DOI: 10.1097/EE9.0000000000000166

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