EconPapers    
Economics at your fingertips  
 

Digital remote monitoring plus usual care versus usual care in patients treated with oral anticancer agents: the randomized phase 3 CAPRI trial

Olivier Mir, Marie Ferrua, Aude Fourcade, Delphine Mathivon, Adeline Duflot-Boukobza, Sarah Dumont, Eric Baudin, Suzette Delaloge (), David Malka, Laurence Albiges, Patricia Pautier, Caroline Robert, David Planchard, Stéphane de Botton, Florian Scotté (), François Lemare, May Abbas, Marilène Guillet, Vanessa Puglisi, Mario Di Palma and Etienne Minvielle ()
Additional contact information
Olivier Mir: DIOPP - Département interdisciplinaire d’organisation des parcours patients - IGR - Institut Gustave Roussy
Marie Ferrua: IGR - Institut Gustave Roussy
Aude Fourcade: IGR - Institut Gustave Roussy
Delphine Mathivon: DIOPP - Département interdisciplinaire d’organisation des parcours patients - IGR - Institut Gustave Roussy
Adeline Duflot-Boukobza: IGR - Institut Gustave Roussy
Sarah Dumont: IGR - Institut Gustave Roussy
Eric Baudin: IGR - Institut Gustave Roussy
Suzette Delaloge: IGR - Institut Gustave Roussy
David Malka: IGR - Institut Gustave Roussy
Laurence Albiges: IGR - Institut Gustave Roussy
Patricia Pautier: IGR - Institut Gustave Roussy
Caroline Robert: IGR - Institut Gustave Roussy
David Planchard: IGR - Institut Gustave Roussy
Stéphane de Botton: IGR - Institut Gustave Roussy
Florian Scotté: DIOPP - Département interdisciplinaire d’organisation des parcours patients - IGR - Institut Gustave Roussy
François Lemare: IGR - Institut Gustave Roussy
May Abbas: DIOPP - Département interdisciplinaire d’organisation des parcours patients - IGR - Institut Gustave Roussy
Marilène Guillet: IGR - Institut Gustave Roussy
Vanessa Puglisi: DIOPP - Département interdisciplinaire d’organisation des parcours patients - IGR - Institut Gustave Roussy
Mario Di Palma: DIOPP - Département interdisciplinaire d’organisation des parcours patients - IGR - Institut Gustave Roussy
Etienne Minvielle: DIOPP - Département interdisciplinaire d’organisation des parcours patients - IGR - Institut Gustave Roussy, CRG I3 - Centre de recherche en gestion i3 - X - École polytechnique - IP Paris - Institut Polytechnique de Paris - Université Paris-Saclay - I3 - Institut interdisciplinaire de l’innovation - CNRS - Centre National de la Recherche Scientifique

Post-Print from HAL

Abstract: Strategies that individualize the care of cancer patients receiving oral anticancer agents offer opportunities to improve treatment adherence and patient care. However, the impact of digital remote monitoring systems in this setting has not been evaluated. Here, we report the results of a phase 3 trial (CAPRI, NCT02828462) to assess the impact of a nurse navigator-led program on treatment delivery for patients with metastatic cancer. Patients receiving approved oral anticancer agents were randomized (1:1) to an intervention combining a nurse navigator-led follow-up system and a web portal–smartphone application on top of usual care, or to usual symptom monitoring at the discretion of the treating oncologist, for a duration of 6 months. The primary objective included optimization of the treatment dose. Secondary objectives were grade ≥3 toxicities, patient experience, rates and duration of hospitalization, response and survival, and quality of life. In 559 evaluable patients the relative dose intensity was higher in the experimental arm (93.4% versus 89.4%, P = 0.04). The intervention improved the patient experience (Patient Assessment of Chronic Illness Care score, 2.94 versus 2.67, P = 0.01), reduced the days of hospitalization (2.82 versus 4.44 days, P = 0.02), and decreased treatment-related grade ≥3 toxicities (27.6% versus 36.9%, P = 0.02). These findings show that patient-centered care through remote monitoring of symptoms and treatment may improve patient outcomes and experience.

Date: 2022
New Economics Papers: this item is included in nep-exp and nep-hea
Note: View the original document on HAL open archive server: https://hal.science/hal-03773192v1
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

Published in Nature Medicine, 2022, 28 (6), pp.1224-1231. ⟨10.1038/s41591-022-01788-1⟩

Downloads: (external link)
https://hal.science/hal-03773192v1/document (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:hal:journl:hal-03773192

DOI: 10.1038/s41591-022-01788-1

Access Statistics for this paper

More papers in Post-Print from HAL
Bibliographic data for series maintained by CCSD ().

 
Page updated 2025-03-19
Handle: RePEc:hal:journl:hal-03773192