Cognitive remediation and professional insertion of people with schizophrenia: RemedRehab, a randomized controlled trial

S. Cervello, J. Dubreucq, M. Trichanh, A. Dubrulle, I. Amado, M. Bralet (), M. Chirio-Espitalier, S. Delille, E. Fakra (), Christian Francq (), N. Guillard-Bouhet, J. Graux, C. Lançon, J. Zakoian, E. Gauthier, C. Demily and N. Franck
Additional contact information
S. Cervello: ISC-MJ - Institut des sciences cognitives Marc Jeannerod - Centre de neuroscience cognitive - UMR5229 - UCBL - Université Claude Bernard Lyon 1 - Université de Lyon - CNRS - Centre National de la Recherche Scientifique
J. Dubreucq: Fondation FondaMental [Créteil]
A. Dubrulle: 149 rue de Bercy - IDELE - Institut de l'élevage
M. Bralet: CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - AP-HP. Université Paris Saclay - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay
E. Fakra: CRNL-PSYR2 - Psychiatric Disorders, Neuroscience Research and Clinical Research - CRNL - Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center - UCBL - Université Claude Bernard Lyon 1 - Université de Lyon - UJM - Université Jean Monnet - Saint-Étienne - Université de Lyon - INSERM - Institut National de la Santé et de la Recherche Médicale - CNRS - Centre National de la Recherche Scientifique, UJM - Université Jean Monnet - Saint-Étienne, CHU ST-E - Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne]
Christian Francq: CREST - Centre de Recherche en Économie et Statistique - ENSAI - Ecole Nationale de la Statistique et de l'Analyse de l'Information [Bruz] - GENES - Groupe des Écoles Nationales d'Économie et Statistique - X - École polytechnique - IP Paris - Institut Polytechnique de Paris - ENSAE Paris - École Nationale de la Statistique et de l'Administration Économique - GENES - Groupe des Écoles Nationales d'Économie et Statistique - IP Paris - Institut Polytechnique de Paris - CNRS - Centre National de la Recherche Scientifique, IP Paris - Institut Polytechnique de Paris
C. Lançon: Hôpitaux Sud - Hôpital Sainte-Marguerite [CHU - APHM], Fondation FondaMental [Créteil]
J. Zakoian: CREST - Centre de Recherche en Economie et Statistique [Bruz] - ENSAI - Ecole Nationale de la Statistique et de l'Analyse de l'Information [Bruz] - GENES - Groupe des Écoles Nationales d'Économie et Statistique, IP Paris - Institut Polytechnique de Paris
E. Gauthier: LCE - Laboratoire Chrono-environnement (UMR 6249) - CNRS - Centre National de la Recherche Scientifique - UFC - Université de Franche-Comté - UBFC - Université Bourgogne Franche-Comté [COMUE], UMLP - Université Marie et Louis Pasteur, IUF - Institut universitaire de France - M.E.N.E.S.R. - Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche
C. Demily: ISC-MJ - Institut des sciences cognitives Marc Jeannerod - Centre de neuroscience cognitive - UMR5229 - UCBL - Université Claude Bernard Lyon 1 - Université de Lyon - CNRS - Centre National de la Recherche Scientifique
N. Franck: ISC-MJ - Institut des sciences cognitives Marc Jeannerod - Centre de neuroscience cognitive - UMR5229 - UCBL - Université Claude Bernard Lyon 1 - Université de Lyon - CNRS - Centre National de la Recherche Scientifique, Réseau Handicap Psychique RéHPSY

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Abstract: Abstract Background People suffering from schizophrenia cannot easily access employment in European countries. Different types of vocational programs coexist in France: supported employment, sheltered employment (ShE), and hybrid vocational programs. It is now acknowledged that the frequent cognitive impairments constitute a major obstacle to employment for people with schizophrenia. However, cognitive remediation (CR) is an evidence-based nonpharmacological treatment for these neurocognitive deficits. Methods RemedRehab was a multicentric randomized comparative open trial in parallel groups conducted in eight centers in France between 2013 and 2018. Participants were recruited into ShE firms before their insertion in employment (preparation phase). They were randomly assigned to cognitive training Cognitive Remediation for Schizophrenia (RECOS) or Treatment As Usual (TAU). The aim of the study was to compare with the benefits of the RECOS program on access to employment and work attendance for people with schizophrenia, measured by the ratio: number of hours worked on number of hours stipulated in the contract. Results Seventy-nine patients were included in the study between October 2018 and September 2019. Fifty-three patients completed the study. Hours worked / planned hours equal to 1 or greater than 1 were significantly higher in the RECOS group than in the TAU group. Conclusions Participants benefited from a RECOS individualized CR program allows a better rate of work attendance in ShE, compared to the ones benefited from TAU. Traditional vocational rehabilitation enhanced with individualized CR in a population of patients with schizophrenia is efficient on work attendance during the first months of work integration.

Date: 2021-04-15
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Published in European Psychiatry, 2021, 64 (1), pp.e31. ⟨10.1192/j.eurpsy.2021.25⟩

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Persistent link: https://EconPapers.repec.org/RePEc:hal:journl:hal-05431336

DOI: 10.1192/j.eurpsy.2021.25

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