Genetic diversity, disease prevalence and the coronavirus pandemic

Andrew Phiri

MPRA Paper from University Library of Munich, Germany

Abstract: The COVID-19 disease outbreak is the deadliest viral pandemic our generation has experienced, and much uncertainty exists over the vulnerability of different populations to the virus since a clinically-approved vaccination does not exist. Our study investigates whether evolutionary processes such as genetic diversity and cultural behaviour norms can explain the differences in COVID-19 virus infections and mortalities observed in different countries. Using a sample of 133 countries we find that populations with higher expected genetic heterozygosity and more historical exposure to infectious diseases are associated with lower COVID-19 infections and mortalities. Further investigations reveal two ‘channels’ of transmission. Firstly, a longer migratory distance from the origins of homo sapiens adversely influences expected heterozygosity, which then increases the populations susceptibility to the COVID_19 virus. Secondly, higher disease prevalence leads to higher collectivism (lower individualism) behaviour, which then reduces the populations susceptibility to COVID_19 infections. Our analysis is robust to the inclusion of additional controls and dummies. Policy implications of our findings are discussed.

Keywords: COVID-19; Expected heterozygosity; Disease prevalence; Collectivism; Individualism; Deep roots. (search for similar items in EconPapers)
JEL-codes: C33 C36 C52 I18 Z1 Z13 (search for similar items in EconPapers)
Date: 2020-06-17
New Economics Papers: this item is included in nep-evo, nep-gro, nep-hea and nep-ore
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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Persistent link: https://EconPapers.repec.org/RePEc:pra:mprapa:101175

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