Economics of Switching from Vial to Disposable Pen Among Insulin Glargine-Treated Patients with Type 2 Diabetes Mellitus

Lin Xie, Steve Zhou, Wenhui Wei, Jasvinder Gill, Chunshen Pan and Onur Baser

MPRA Paper from University Library of Munich, Germany

Abstract: Objective: The study was designed to evaluate real-world data on clinical and economic outcome differences between patients with type 2 diabetes mellitus (T2DM) who use insulin glargine with vial-and-syringe delivery and those who switch to pen administration. Subjects and Methods: This retrospective study analyzed medical and pharmacy claims information from the national managed-care IMPACT® database (Ingenix Inc., Salt Lake City, UT). Adults with T2DM treated with insulin glargine were evaluated. Clinical and economic outcomes over 1 year were compared between individuals who had converted from administering glargine via vial-and-syringe to the SoloSTAR® (sanofi-aventis U.S., Bridgewater, NJ) pen (Switchers) and patients who continued to use vial-and-syringe administration (Continuers). Patients from each cohort were matched using propensity score matching for a comparison sample. Results: In total, 3,893 eligible patients were identified (665 Switchers and 3,228 Continuers), with a matched cohort with 603 patients in each group. Baseline characteristics were similar between groups. One-year treatment persistence was signifi-cantly higher with Switchers versus Continuers (65.3% vs. 49.8%; P

Keywords: Vial to Disposable Pen; Insulin Glargine-Treated Patients; Diabetes Mellitus (search for similar items in EconPapers)
JEL-codes: C0 I1 (search for similar items in EconPapers)
Date: 2013
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Published in Diabetes Technology & Therapeutics 3.15(2013): pp. 230-236

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