Measurement of Cumulative Physiological Dysregulation in an Older Population

Christopher Seplaki, Noreen Goldman, Maxine Weinstein and Yu-Hsuan Lin
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Christopher Seplaki: Princeton University
Noreen Goldman: Princeton University
Maxine Weinstein: Georgetown University
Yu-Hsuan Lin: Bureau of Health Promotion, Center for Population and Survey Research, Department of Health, Taichung, Taiwan

No 295, Working Papers from Princeton University, Woodrow Wilson School of Public and International Affairs, Office of Population Research.

Abstract: Theories of allostatic load postulate that an important pathway connecting the social environment with health involves biological responses to stressful stimuli and subsequent dysregulation of interrelated physiological systems. We formulate a new measure for cumulative physiological dysregulation using a grade of membership model estimated with biodemographic data from a national sample of older Taiwanese. We investigate associations between the measure and physical, psychological, and cognitive function. The results provide insights into the relationships between a set of biological profiles and various health outcomes, identify limitations of earlier approaches, and underscore next steps in the development of improved formulations of physiological dysregulation.

JEL-codes: I10 (search for similar items in EconPapers)
Date: 2004-02
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