Cost of Poor Adherence to Anti-Hypertensive Therapy in Europe

Francesco Saverio Mennini, Andrea Marcellusi (), Johann Graf von der Schulenburg, Alastair Gray, Pierre L. Levy (), Paolo Sciattella (), Marco Soro (), Gianandrea Staffiero (), Jan Zeidler (), Aldo Maggioni () and Roland.E. Schmieder ()
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Pierre L. Levy: PSL-Université Paris-Dauphine
Paolo Sciattella: CEIS University of Rome “Tor Vergata”
Marco Soro: Market Access Dept. - Daiichi Sankyo Europe, Munich
Gianandrea Staffiero: Department of Economics and Business, CRES, Universitat Pompeu Fabra Barcelona
Jan Zeidler: Center for Health Economics Research Hannover(CHERH),Leibniz Universität Hannover
Aldo Maggioni: Associazione Nazionale Medici Cardiologi Ospedalieri Research Center, Florence
Roland.E. Schmieder: Department of Nephrology and Hypertension, University Hospital Erlangen

No 299, CEIS Research Paper from Tor Vergata University, CEIS

Abstract: Background: The financial burden for EU health systems associated with cardiovascular disease has been estimated to be nearly € 110 billion in 2006, corresponding to 10% of total healthcare expenditure across EU or a mean € 223 annual cost per capita. The main purpose of this study is to estimate the costs related to hypertension and the economic impact of increasing adherence to anti-hypertensive therapy in 5 European countries (Italy, Germany, France, Spain and England). Methods: A probabilistic prevalence-based decision tree model was developed to estimate the direct costs of cardiovascular disease related to hypertension (CV defined as: stroke, heart attack, kidney disease, heart failure) in 5 European countries. Our model considered adherence to hypertension treatment as a main driver of blood pressure control (BP

Pages: 19 pages
Date: 2013-12-13, Revised 2013-12-13
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