Survival of the weakest? Culling evidence from the 1918 flu pandemic
Harald Mayr (),
Kaspar Staub and
Ulrich Woitek ()
No 316, ECON - Working Papers from Department of Economics - University of Zurich
When a negative shock aﬀects a cohort in utero, two things may happen: ﬁrst, the population suffers detrimental consequences in later life; and second, some will die as a consequence of the shock, either in utero or early in life. The latter effect, often referred to as culling, may induce a bias in estimates of later life outcomes. When the health shock disproportionately affects a positively selected subpopulation, the long-term effects are overestimated. The 1918 ﬂu pandemic was plausibly more harmful to mothers of high socioeconomic status, as a suppressed immune system in mothers of low socioeconomic status may have been protective against the most severe consequences of infection. Using historical birth records from the city of Bern, Switzerland, we assess this concern empirically and document that a careful consideration of culling is paramount for the evaluation of the 1918 ﬂu pandemic and other fetal health shocks.
Keywords: Fetal origins hypothesis; 1918 ﬂu pandemic; culling; survivorship bias (search for similar items in EconPapers)
JEL-codes: I10 I15 I18 N34 J24 (search for similar items in EconPapers)
New Economics Papers: this item is included in nep-hea and nep-his
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Persistent link: https://EconPapers.repec.org/RePEc:zur:econwp:316
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