TITEBETA: Stata module to conduct toxicity monitoring for phase 2 (and 3) trials

E. Paul Wileyto ()
Additional contact information
E. Paul Wileyto: University of Pennsylvania

Statistical Software Components from Boston College Department of Economics

Abstract: titebeta is a routine for safety monitoring of late onset toxicities in phase 2 (and 3) clinical trials. It calculates the posterior probability that the toxicity event rate exceeds a limit, based on censored data for toxicities and a beta prior. Data are entered as a list of two variables, with the first depvar being a 0/1 toxicity outcome, and the second {indepvar} being an elapsed time variable. The calculation uses the weighting scheme described by Cheung & Thall (Biometrics, 2002), for the simple case that considers only toxicity monitoring, and not complex trial outcomes.

Language: Stata
Requires: Stata version 16
Keywords: toxicity; clinical trials; monitoring; beta prior (search for similar items in EconPapers)
Date: 2023-07-07
Note: This module should be installed from within Stata by typing "ssc install titebeta". The module is made available under terms of the GPL v3 (https://www.gnu.org/licenses/gpl-3.0.txt). Windows users should not attempt to download these files with a web browser.
References: Add references at CitEc
Citations:

Downloads: (external link)
http://fmwww.bc.edu/repec/bocode/t/titebeta.ado program code (text/plain)
http://fmwww.bc.edu/repec/bocode/t/titebeta.sthlp help file (text/plain)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:boc:bocode:s459217

Ordering information: This software item can be ordered from
http://repec.org/docs/ssc.php

Access Statistics for this software item

More software in Statistical Software Components from Boston College Department of Economics Boston College, 140 Commonwealth Avenue, Chestnut Hill MA 02467 USA. Contact information at EDIRC.
Bibliographic data for series maintained by Christopher F Baum ().