NSTAGEBIN: Stata module to provide facilities for optimising and designing multi-arm multi-stage (MAMS) randomised controlled trials with binary outcomes

Babak Choodari-Oskooei (), Daniel J. Bratton () and Mahesh KB Parmar ()
Additional contact information
Babak Choodari-Oskooei: MRC Clinical Trials Unit at UCL, London, UK
Daniel J. Bratton: Clinical Statistics, GlaxoSmithKline, Stevenage, UK
Mahesh KB Parmar: MRC Clinical Trials Unit at UCL, London, UK

Statistical Software Components from Boston College Department of Economics

Abstract: nstagebin specifies the design (sample size, duration and overall pairwise operating characteristics) of a multi-arm, multi-stage (MAMS) trial using a binary intermediate (I) outcome at the interim stages and a binary definitive (D) outcome at the final stage, both analysed using an absolute difference in proportions. See Bratton, Phillips & Parmar (2013) for a description of the design and Royston, Barthel, Parmar, Oskooei & Isham (2011) for a description of a similar MAMS design for time-to-event outcomes.

Language: Stata
Requires: Stata version 10
Keywords: clinical trials; sample size; multi-stage trial (search for similar items in EconPapers)
Date: 2023-09-28
Note: This module should be installed from within Stata by typing "ssc install nstagebin". The module is made available under terms of the MIT license (https://opensource.org/licenses/MIT).
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http://fmwww.bc.edu/repec/bocode/n/nstagebin.ado program code (text/plain)
http://fmwww.bc.edu/repec/bocode/n/nstagebinopt.ado program code (text/plain)
http://fmwww.bc.edu/repec/bocode/n/nstagebin.dlg program code (text/plain)
http://fmwww.bc.edu/repec/bocode/n/nstagebin.sthlp help file (text/plain)
http://fmwww.bc.edu/repec/bocode/n/nstagebinopt.sthlp help file (text/plain)
http://fmwww.bc.edu/repec/bocode/n/nstagebin_example.do sample do-file (text/plain)

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