A synthesis of pathways linking diet, metabolic risk and cardiovascular disease: a framework to guide further research and approaches to evidence-based practice

Marjorie Rafaela Lima do Vale, Luke Buckner, Claudia Gabriela Mitrofan, Claudia Raulino Tramontt, Sento Kai Kargbo, Ali Khalid, Sammyia Ashraf, Saad Mouti, Xiaowu Dai, David Unwin, Jeffrey Bohn, Lisa Goldberg, Rajna Golubic and Sumantra Ray

Department of Economics, Working Paper Series from Department of Economics, Institute for Business and Economic Research, UC Berkeley

Abstract: Cardiovascular disease (CVD) is the most common non-communicable disease occurring globally. Although previous literature has provided useful insights into the important role that diet plays in CVD prevention and treatment, understanding the causal role of diets is a difficult task considering inherent and introduced weaknesses of observational (e.g. not properly addressing confounders and mediators) and experimental research designs (e.g. not appropriate or well designed). In this narrative review, we organised current evidence linking diet, as well as conventional and emerging physiological risk factors, with CVD risk, incidence and mortality in a series of diagrams. The diagrams presented can aid causal inference studies as they provide a visual representation of the types of studies underlying the associations between potential risk markers/factors for CVD. This may facilitate the selection of variables to be considered and the creation of analytical models. Evidence depicted in the diagrams was systematically collected from studies included in the British Nutrition Task Force report on diet and CVD and database searches, including Medline and Embase. Although several markers and disorders linked to conventional and emerging risk factors for CVD were identified, the causal link between many remains unknown. There is a need to address the multifactorial nature of CVD and the complex interplay between conventional and emerging risk factors with natural and built environments, while bringing the life course into the spotlight.

Keywords: Biomedical and Clinical Sciences; Nutrition and Dietetics; Nutrition; Prevention; Heart Disease; Cardiovascular; 2.3 Psychological; social and economic factors; Aetiology; Generic health relevance; Good Health and Well Being; Humans; Cardiovascular Diseases; Diet; Risk Factors; Nutritional Status; Evidence-Based Practice; Causality; Cardiovascular disease; Review; Risk factors; Nutritional status; Biological Sciences; Agricultural and Veterinary Sciences; Medical and Health Sciences; Nutrition & Dietetics; Nutrition and dietetics (search for similar items in EconPapers)
Date: 2023-12-01
New Economics Papers: this item is included in nep-agr
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.escholarship.org/uc/item/0fv1v1c1.pdf;origin=repeccitec (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:cdl:econwp:qt0fv1v1c1

Access Statistics for this paper

More papers in Department of Economics, Working Paper Series from Department of Economics, Institute for Business and Economic Research, UC Berkeley Contact information at EDIRC.
Bibliographic data for series maintained by Lisa Schiff ().