Cost-effectiveness analysis of thermotherapy versus pentava-lent antimonials for the treatment of cutaneous leishmaniasis

Mery Tamayo Plata (), Jaiberth Antonio Cardona-Arias (), Liliana López Carvajal () and Iván Darío Vélez ()

No 16361, Documentos de Trabajo de Valor Público from Universidad EAFIT

Abstract: Introduction: The treatment of cutaneous leishmaniasis is toxic, has contraindications and a high cost. Objective: To estimate the cost-effectiveness of thermotherapy versus pentavalent antimonials for the treatment of cutaneous leishmaniasis. Methods: Effectiveness was the proportion of healing, and safety with the adverse effects; these parameters were estimated from a controlled clinical trial and a meta-analysis. A standard costing were conducted. Average and incremental cost-effectiveness ratios were estimated. The uncertainty regarding effectiveness, safety and costs was determined through sensitivity analyses. Results: The total costs were $66,807 with Glucantime and $14,079 with thermotherapy. The therapeutic effectiveness rates were 64.2% for thermotherapy and 85.1% for Glucantime. The average cost-effectiveness ratios ranged between $721 and $1,275 for Glucantime and between $187 and $390 for thermotherapy. Based on the meta-analysis thermotherapy may be a dominant strategy. Conclusion: The excellent cost-effectiveness ratio of thermotherapy shows the relevance of its inclusion in guidelines for the treatment.

Keywords: Cost-Effectiveness; AnalysisCutaneous; LeishmaniasisThermotherapyAntimony; Sodium; GluconateColombia (search for similar items in EconPapers)
Pages: 22
Date: 2018-02-01
New Economics Papers: this item is included in nep-hea
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Persistent link: https://EconPapers.repec.org/RePEc:col:000122:016361

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