Powerful tools for productivity improvements in microalgal production

Han Sun, Tao Wu, Stephenie Hiu Yuet Chen, Yuanyuan Ren, Shufang Yang, Junchao Huang, Haijin Mou and Feng Chen

Renewable and Sustainable Energy Reviews, 2021, vol. 152, issue C

Abstract: Technology for microalgae cultivation has potential to maximize biomass generation to production process and economic viability of microalgal production. Powerful tools that increase the production and value of microalgae are therefore of great significance. In this review, valid approaches involved in strain screening, microalgal cultivation, cell harvesting and disruption are discussed with regards to productivity improvements and energy efficiency. Particularly, current research in kinetic models, metabolic flux analysis and genetic tools are considered. Kinetic models of nutrient, light, temperature and cell quota to increase the biomass concentration and targeted products are discussed. Metabolic flux analysis, especially GC–MS-based 13C-metabolic flux analysis is discussed to describe how the central carbon flux to targeted products can be precisely and rapidly engineered. This approach is exemplified by Chromochloris zofingiensis under batch and fed-batch cultures. Molecular approaches including gene silencing methods and CRISPR–Cas9 are also discussed as these provide powerful tools for enhanced production of biomass and associated lipids and carotenoids. Finally, the huge potential of combined applications of the described tools are discussed. A better understanding of cell behavior in response to these tools will provide the means to improve microalgal production at a competitive cost.

Keywords: Microalgal production; Productivity improvement; Kinetic model; Metabolic flux analysis; Genetic tool; Lipid biosynthesis (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
http://www.sciencedirect.com/science/article/pii/S1364032121008856
Full text for ScienceDirect subscribers only

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:eee:rensus:v:152:y:2021:i:c:s1364032121008856

Ordering information: This journal article can be ordered from
http://www.elsevier.com/wps/find/journaldescription.cws_home/600126/bibliographic
http://www.elsevier. ... 600126/bibliographic

DOI: 10.1016/j.rser.2021.111609

Access Statistics for this article

Renewable and Sustainable Energy Reviews is currently edited by L. Kazmerski

More articles in Renewable and Sustainable Energy Reviews from Elsevier
Bibliographic data for series maintained by Catherine Liu ().