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Asthma burden according to treatment steps in the French population-based cohort CONSTANCES

Nicolas Roche, Rachel Nadif (), Caroline Fabry-Vendrand, Laura Pillot, Gabriel Thabut, Clément Teissier, Stéphane Bouée (), Marcel Goldberg and Marie Zins
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Nicolas Roche: CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay, Service de pneumologie [CHU Cochin] - Hôpital Cochin [AP-HP] - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP), IC UM3 (UMR 8104 / U1016) - Institut Cochin - INSERM - Institut National de la Santé et de la Recherche Médicale - CNRS - Centre National de la Recherche Scientifique - UPCité - Université Paris Cité
Rachel Nadif: CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay
Marcel Goldberg: CONSTANCES - Cohortes épidémiologiques en population - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay - UPCité - Université Paris Cité
Marie Zins: CONSTANCES - Cohortes épidémiologiques en population - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay - UPCité - Université Paris Cité

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Abstract: Background: Data on health care consumption and costs of asthma in the French population are scarce. Objectives: The study objective was to describe the burden of asthma according to GINA treatment steps in the CONSTANCES cohort. Methods: Data from 162,725 participants included between 2012 and 2019 were extracted. Participants were considered as current asthmatics if asthma was reported at inclusion and asthma symptoms and/or treatments were reported in 2019. Participants were classified in three categories according to GINA treatment steps. The results were compared to non-asthmatic participants matched with a propensity score calculated on age, sex, region of residence, precariousness score and year of inclusion. Results: Among 162,725 participants aged 18–69 years, 6783 asthmatics (1566 not treated for asthma, 2444 + 251 GINA steps 1 + 2, 1054 + 1315 GINA steps 3 + 4, and 153 GINA step 5) were matched with 6783 controls. Average annual ambulatory cost and average annual hospitalization cost were respectively €1925 and €719 for asthmatics versus €1376 and €511 for participants without asthma (p

Keywords: Asthma; Burden of disease; CONSTANCES; Economic evaluation; France; GINA; SNDS; Treatment steps (search for similar items in EconPapers)
Date: 2023
New Economics Papers: this item is included in nep-hea
Note: View the original document on HAL open archive server: https://hal.science/hal-03949592
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Published in Respiratory Medicine, 2023, 206, ⟨10.1016/j.rmed.2022.107057⟩

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Persistent link: https://EconPapers.repec.org/RePEc:hal:journl:hal-03949592

DOI: 10.1016/j.rmed.2022.107057

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