Computer Simulation of Noise Effects of the Neighborhood of Stimulus Threshold for a Mathematical Model of Homeostatic Regulation of Sleep-Wake Cycles

Wuyin Jin, Qian Lin, An Wang and Chunni Wang

Complexity, 2017, vol. 2017, 1-7

Abstract:

The noise effects on a homeostatic regulation of sleep-wake cycles’ neuronal mathematical model determined by the hypocretin/orexin and the local glutamate interneurons spatiotemporal behaviors are studied within the neighborhood of stimulus threshold in this work; the neuronal noise added to the stimulus, the conductance, and the activation variable of the modulation function are investigated, respectively, based on a circadian input skewed in sine function. The computer simulation results suggested that the increased amplitude of external current input will lead to the fact that awakening time is advanced but the sleepy time remains the same; for the bigger conductance and modulation noise, the regulatory mechanism of the model sometimes will be collapsed and the coupled two neurons of the model show very irregular activities; the falling asleep or wake transform appears at nondeterminate time.

Date: 2017
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (3)

Downloads: (external link)
http://downloads.hindawi.com/journals/8503/2017/4797545.pdf (application/pdf)
http://downloads.hindawi.com/journals/8503/2017/4797545.xml (text/xml)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:hin:complx:4797545

DOI: 10.1155/2017/4797545

Access Statistics for this article

More articles in Complexity from Hindawi
Bibliographic data for series maintained by Mohamed Abdelhakeem ().